Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors
BMC Cancer. 2013 Aug 10;13:382. doi: 10.1186/1471-2407-13-382. ABSTRACT BACKGROUND: Cisplatin (CDDP) resistance in testicular germ cell tumors (GCTs) is still a clinical challenge, and one associated with poor prognosis. The purpose of this work was to test pazopanib, an anti-tumoral and anti-angiogenic multikinase inhibitor, and its combination with lapatinib (an anti-ErbB inhibitor) in mouse orthotopic […]








