Transforming cancer drug discovery with Big Data and AI
Expert Opin Drug Discov. 2019 Nov;14(11):1089-1095. doi: 10.1080/17460441.2019.1637414.…
Meeting Proceedings from ICBS 2018- Toward Translational Impact
ACS Chem Biol. 2019 Apr 19;14(4):567-578. doi: 10.1021/acschembio.9b00169.…
canSAR: update to the cancer translational research and drug discovery knowledgebase
Nucleic Acids Res. 2019 Jan 8;47(D1):D917-D922. doi: 10.1093/nar/gky1129.ABSTRACTcanSAR…
Dual Inhibitors of PARPs and ROCKs
ACS Omega. 2018 Oct 31;3(10):12707-12712. doi: 10.1021/acsomega.8b02337.…
Objective, Quantitative, Data-Driven Assessment of Chemical Probes
Cell Chem Biol. 2018 Feb 15;25(2):194-205.e5. doi: 10.1016/j.chembiol.2017.11.004.…
Polypharmacology in Precision Oncology: Current Applications and Future Prospects
Curr Pharm Des. 2016;22(46):6935-6945. doi: 10.2174/1381612822666160923115828.ABSTRACTOver…
canSAR: an updated cancer research and drug discovery knowledgebase
Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030.…
In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals targeting opportunities
Cancer Cell. 2015 Mar 9;27(3):382-96. doi: 10.1016/j.ccell.2015.02.007.ABSTRACTLarge…
Distant polypharmacology among MLP chemical probes
ACS Chem Biol. 2015 Feb 20;10(2):395-400. doi: 10.1021/cb500393m.…
Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors
Oncotarget. 2014 May 30;5(10):3023-8. doi: 10.18632/oncotarget.1814.ABSTRACTPARP…
Exploring the effect of PARP-1 flexibility in docking studies
J Mol Graph Model. 2013 Sep;45:192-201. doi: 10.1016/j.jmgm.2013.08.006.…
Identification of pim kinases as novel targets for PJ34 with confounding effects in PARP biology
ACS Chem Biol. 2012 Dec 21;7(12):1962-7. doi: 10.1021/cb300317y.…
