SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade
Nat Commun. 2021 Jul 14;12(1):4319. doi: 10.1038/s41467-021-24618-3.ABSTRACTDespite…
SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade
Nat Commun. 2021 Jul 14;12(1):4319. doi: 10.1038/s41467-021-24618-3.ABSTRACTDespite…
Lung Cancer Management with Silibinin: A Historical and Translational Perspective
Pharmaceuticals (Basel). 2021 Jun 11;14(6):559. doi: 10.3390/ph14060559.ABSTRACTThe…
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis
J Clin Invest. 2021 Jul 1;131(13):e152424. doi: 10.1172/JCI152424.NO…
Bivalent chromatin as a therapeutic target in cancer: An in silico predictive approach for combining epigenetic drugs
PLoS Comput Biol. 2021 Jun 21;17(6):e1008408. doi: 10.1371/journal.pcbi.1008408.…
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair
Oncogene. 2021 Aug;40(31):5042-5048. doi: 10.1038/s41388-021-01879-2.…
KEYNOTE-921: Phase III study of pembrolizumab plus docetaxel for metastatic castration-resistant prostate cancer
Future Oncol. 2021 Sep;17(25):3291-3299. doi: 10.2217/fon-2020-1133.…
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases
Mol Cancer. 2021 Jun 6;20(1):86. doi: 10.1186/s12943-021-01370-2.ABSTRACTBACKGROUND:…
SEGHI Study: Defining the Best Surveillance Strategy in Hodgkin Lymphoma after First-Line Treatment
Cancers (Basel). 2021 May 17;13(10):2412. doi: 10.3390/cancers13102412.ABSTRACTThe…
The Blockade of Tumoral IL1β-Mediated Signaling in Normal Colonic Fibroblasts Sensitizes Tumor Cells to Chemotherapy and Prevents Inflammatory CAF Activation
Int J Mol Sci. 2021 May 7;22(9):4960. doi: 10.3390/ijms22094960.ABSTRACTHeterotypic…
Evolution of kinase polypharmacology across HSP90 drug discovery
Cell Chem Biol. 2021 Oct 21;28(10):1433-1445.e3. doi: 10.1016/j.chembiol.2021.05.004.…
Mammary epithelial cells have lineage-rooted metabolic identities
Nat Metab. 2021 May;3(5):665-681. doi: 10.1038/s42255-021-00388-6.…
